It is obvious to me that a recasting of physics is needed. This can be seen conceptually by saying that quantum mechanics is incompatible with general relativity, so one of them, at least, is wrong. On the observational side, anomalies are piling up, and some of them, like the anomalous dynamics of globular clusters, cannot hope to be explained by dark matter. Yet, there is still a huge stigma in physics against alternative theories. If you like, the ecosystem has too little diversity to be healthy. It seems that physicists today confronted with a fascinating anomaly will do anything: propose invisible matter or dimensions, rather than changing the core of Einstein's theories. This is even stranger since Einstein himself believed physics was incomplete & riddled with inconsistency.
I have a humourous analogy, to cheer me up on bad days, that some mainstream physicists are doing 'zombie physics'. The definition of a zombie: "a hypnotized person bereft of consciousness and self-awareness, yet ambulant and able to respond to surrounding stimuli." This is rather unfair, but I do think there is an important point here. Many career-minded physicists have been hypnotized by peer pressure, and are scared of thinking for themselves, being labelled as cranks & damaging their careers. This is making physics dull and sterile, & holding back human progress.
As a first solution I would like to propose a conference, that harks back to the Solvay conferences of the earlier 20th century, when physicists were bold and creative. This FreePhysics conference would invite the creators of new theories, but only if they agree to apply the theories to real anomalies. The theories could then all be objectively ranked depending on 1) their agreement with all the data, 2) simplicity and 3) self-consistency. I suspect it would be a noisy affair! Anyone want to second this?
Great things are done more through courage than through wisdom - German/English saying.